| Gene Information | |
|---|---|
| Gene Name | CDC14B |
| Organism | Homo sapiens (Human) |
| Gene Length | 498 |
| Protein Names | Dual specificity protein phosphatase CDC14B (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000081377 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O60729 |
| Gene Card | CDC14B |
| Uniprot ID | O60729 |
| Pfam | PF00782; PF14671 |
| In ASD | no |
| Allosteric Prediction | no (-0.855925749) |
| Ortholog in Animals | Alpaca_ CDC14B ( ortholog_one2one ) Macaque_ CDC14B ( ortholog_one2one ) Rabbit_ CDC14B ( ortholog_one2one ) |
| Ohnologs | CDC14A |
| Paralogs | CDC14A, PTP4A3, PTP4A1, CDKN3, PTPDC1, PTP4A2, PALD1, CDC14C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1OHC (X-ray 2.50A ) 1OHD (X-ray 2.60A ) 1OHE (X-ray 2.20A ) |
| DBSNP | rs16911114 rs16911075 |
| Subcellular location [CC] | Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Following DNA damage, translocates from the nucleolus to the nucleoplasm and interacts with FZR1/CDH1. |
| Mouse PG classification | NA |
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