| Gene Information | |
|---|---|
| Gene Name | ZCWCC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 939 |
| Protein Names | MORC family CW-type zinc finger protein 3 (Nuclear matrix protein 2) (Zinc finger CW-type coiled-coil domain protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14149 |
| Gene Card | MORC3 |
| Uniprot ID | Q14149 |
| Pfam | PF17942; PF07496 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney. {ECO:0000269|PubMed:11927593}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4QQ4 (X-ray 1.75A ) 5SVI (X-ray 1.61A ) 5SVX (X-ray 1.56A ) 5SVY (X-ray 1.05A ) 6O1E (X-ray 2.41A ) 6O5W (X-ray 1.41A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:11927593, ECO:0000269|PubMed:17332504}. Nucleus matrix {ECO:0000269|PubMed:11927593, ECO:0000269|PubMed:20501696}. Nucleus, PML body {ECO:0000269|PubMed:17332504, ECO:0000269|PubMed:27440897}. Chromosome {ECO:0000250|UniProtKB:F7BJB9}. Note=Also found in PML-independent nuclear bodies. Localization to nuclear bodies is ATP-dependent. {ECO:0000269|PubMed:20501696}. |
| Mouse PG classification | NA |
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