| Gene Information | |
|---|---|
| Gene Name | PTPRM |
| Organism | Homo sapiens (Human) |
| Gene Length | 1452 |
| Protein Names | Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000173482 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P28827 |
| Gene Card | PTPRM |
| Uniprot ID | P28827 |
| Pfam | PF00041; PF00047; PF00629; PF00102 |
| In ASD | no |
| Allosteric Prediction | no (-0.034369713) |
| Ortholog in Animals | Alpaca_ PTPRM ( ortholog_one2one ) Dog_ PTPRM ( ortholog_one2one ) GuineaPig_ PTPRM ( ortholog_one2one ) Macaque_ PTPRM ( ortholog_one2one ) Mouse_ Ptprm ( ortholog_one2one ) Pig_ PTPRM ( ortholog_one2one ) Rat_ Ptprm ( ortholog_one2one ) Rabbit_ PTPRM ( ortholog_one2one ) |
| Ohnologs | PTPRT, PTPRU, PTPRK |
| Paralogs | PTPN12, PTPRC, PTPN6, PTPN18, PTPN7, PTPN1, PTPN13, PTPRF, PTPRK, PTPRB, PTPRA, PTPN22, PTPRG, PTPRR, PTPN5, PTPN23, PTPRZ1, PTPN9, PTPRE, PTPN4, PTPRT, PTPRS, PTPRD, PTPN2, PTPRO, PTPRJ, PTPN11, PTPN20, PTPRU, PTPN14, PTPN3, PTPRN, PTPRN2, PTPRH, PTPN21 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1RPM (X-ray 2.30A ) 2C9A (X-ray 2.70A ) 2V5Y (X-ray 3.10A ) |
| DBSNP | rs35224276 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10753936}; Single-pass type I membrane protein. Note=Localizes in regions of cell-cell contact. {ECO:0000269|PubMed:10753936}. |
| Mouse PG classification | NA |
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