| Gene Information | |
|---|---|
| Gene Name | CMYA4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 931 |
| Protein Names | Protein unc-45 homolog B (Unc-45B) (SMUNC45) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8IWX7 |
| Gene Card | UNC45B |
| Uniprot ID | Q8IWX7 |
| Pfam | PF11701 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in eye lens tissues. Expressed in muscle (at protein level) (PubMed:33217308). {ECO:0000269|PubMed:24549050, ECO:0000269|PubMed:33217308}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.014286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16970659 rs35749208 rs41389545 rs775340790 rs370424081 rs11654824 |
| Subcellular location [CC] | Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:Q6DGE9}. Cytoplasm, myofibril, sarcomere, A band {ECO:0000269|PubMed:33217308}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q6DGE9}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8CGY6}. Note=Expressed at the Z line and in the perinuclear region of myofibrils. Translocates to the A band in response to stress conditions and fibril damage. {ECO:0000250|UniProtKB:Q6DGE9}. |
| Mouse PG classification | NA |
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