| Gene Information | |
|---|---|
| Gene Name | JUN |
| Organism | Homo sapiens (Human) |
| Gene Length | 331 |
| Protein Names | Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39) |
| Target Name | transcription factor ap-1 |
| Target Type | Discontinued target |
| Gene Age | 680 ( ENSG00000177606 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P05412 |
| Gene Card | JUN |
| Uniprot ID | P05412 |
| Pfam | PF00170; PF03957 |
| In ASD | no |
| Allosteric Prediction | yes (1.106974013) |
| Ortholog in Animals | Dog_ JUN ( ortholog_one2one ) GuineaPig_ JUN ( ortholog_one2one ) Macaque_ JUN ( ortholog_one2one ) Mouse_ Jun ( ortholog_one2one ) Pig_ JUN ( ortholog_one2one ) Rat_ Jun ( ortholog_one2one ) Rabbit_ JUN ( ortholog_one2one ) |
| Ohnologs | JUND, JUNB |
| Paralogs | JUNB, JUND |
| Tissue | NA |
| Tissue Specificity | Expressed in the developing and adult prostate and prostate cancer cells. {ECO:0000269|PubMed:24263171, ECO:0000269|PubMed:24559171}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.418454(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A02 (X-ray 2.70A ) 1FOS (X-ray 3.05A ) 1JNM (X-ray 2.20A ) 1JUN (NMR - ) 1S9K (X-ray 3.10A ) 1T2K (X-ray 3.00A ) 5FV8 (X-ray 1.99A ) 5T01 (X-ray 1.89A ) 6Y3V (X-ray 1.50A ) |
| DBSNP | rs9989 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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