| Gene Information | |
|---|---|
| Gene Name | CMPK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 196 |
| Protein Names | UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK) |
| Target Name | ump-cmp kinase |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000162368 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P30085 |
| Gene Card | CMPK1 |
| Uniprot ID | P30085 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.521433823) |
| Ortholog in Animals | Alpaca_ CMPK1 ( ortholog_one2one ) Dog_ CMPK1 ( ortholog_one2one ) GuineaPig_ CMPK1 ( ortholog_one2one ) Mouse_ Cmpk1 ( ortholog_one2one ) Pig_ CMPK1 ( ortholog_one2one ) Rat_ Cmpk1 ( ortholog_one2one ) Rabbit_ CMPK1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AK5, AK1, AK7, AK3, AK9, AK2, AK8, AK4, AK4P3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:11681623}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.054545(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TEV (X-ray 2.10A ) 7E9V (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|HAMAP-Rule:MF_03172, ECO:0000269|PubMed:10462544, ECO:0000269|PubMed:11912132}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03172, ECO:0000269|PubMed:10462544, ECO:0000269|PubMed:11912132}. Note=Predominantly cytoplasmic, less than 15% nuclear. {ECO:0000269|PubMed:11912132}. |
| Mouse PG classification | NA |
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