| Gene Information | |
|---|---|
| Gene Name | CMG2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 489 |
| Protein Names | Anthrax toxin receptor 2 (Capillary morphogenesis gene 2 protein) (CMG-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P58335 |
| Gene Card | ANTXR2 |
| Uniprot ID | P58335 |
| Pfam | PF05586; PF05587; PF00092 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in prostate, thymus, ovary, testis, pancreas, colon, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, skeletal muscle, small intestine and spleen. {ECO:0000269|PubMed:14508707}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1SHT (X-ray 1.81A ) 1SHU (X-ray 1.50A ) 1T6B (X-ray 2.50A ) 1TZN (X-ray 4.30A ) 7N1O (X-ray 2.77A ) |
| DBSNP | rs886041401 rs137852902 rs137852905 rs781637328 rs137852903 rs12647691 rs137852901 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:12700348}; Single-pass type I membrane protein {ECO:0000255}. Note=Expressed at the cell surface. {ECO:0000269|PubMed:12700348}.; [Isoform 2]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:11683410}; Single-pass type I membrane protein {ECO:0000255}. Note=Expressed predominantly within the endoplasmic reticulum and not at the plasma membrane. {ECO:0000269|PubMed:11683410}.; [Isoform 3]: Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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