| Gene Information | |
|---|---|
| Gene Name | DDAH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 285 |
| Protein Names | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH-1) (Dimethylarginine dimethylaminohydrolase 1) (EC 3.5.3.18) (DDAHI) (Dimethylargininase-1) |
| Target Name | n(g),n(g)-dimethylarginine dimethylaminohydrolase 1 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000153904 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O94760 |
| Gene Card | DDAH1 |
| Uniprot ID | O94760 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.166264178) |
| Ortholog in Animals | Alpaca_ DDAH1 ( ortholog_one2one ) Dog_ DDAH1 ( ortholog_one2one ) GuineaPig_ DDAH1 ( ortholog_one2one ) Macaque_ DDAH1 ( ortholog_one2one ) Mouse_ Ddah1 ( ortholog_one2one ) Pig_ DDAH1 ( ortholog_one2one ) Rat_ Ddah1 ( ortholog_one2one ) Rabbit_ DDAH1 ( ortholog_one2one ) |
| Ohnologs | DDAH2 |
| Paralogs | DDAH2 |
| Tissue | NA |
| Tissue Specificity | Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. {ECO:0000269|PubMed:10493931}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JAI (X-ray 2.30A ) 2JAJ (X-ray 2.00A ) 3I2E (X-ray 2.03A ) 3I4A (X-ray 1.90A ) 3P8E (X-ray 2.49A ) 3P8P (X-ray 2.50A ) 6DGE (X-ray 1.91A ) 6SZP (X-ray 1.76A ) 6SZQ (X-ray 2.41A ) 7USZ (X-ray 1.65A ) 7UT0 (X-ray 1.68A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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