| Gene Information | |
|---|---|
| Gene Name | CLPB |
| Organism | Homo sapiens (Human) |
| Gene Length | 707 |
| Protein Names | Caseinolytic peptidase B protein homolog (EC 3.6.1.-) (Suppressor of potassium transport defect 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000162129 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H078 |
| Gene Card | CLPB |
| Uniprot ID | Q9H078 |
| Pfam | PF07724; PF12796; PF13857; PF10431 |
| In ASD | no |
| Allosteric Prediction | yes (0.078325189) |
| Ortholog in Animals | Alpaca_ CLPB ( ortholog_one2one ) Dog_ CLPB ( ortholog_one2one ) GuineaPig_ CLPB ( ortholog_one2one ) Macaque_ CLPB ( ortholog_one2one ) Mouse_ Clpb ( ortholog_one2one ) Pig_ CLPB ( ortholog_one2one ) Rat_ Clpb ( ortholog_one2one ) Rabbit_ CLPB ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | Widely expressed (at protein level) (PubMed:25597511). Expressed in fetal, as well as in adult tissues, with highest levels in adult brain, including thalamus, hippocampus, occipital cortex and parietal cortex. Low expression in granulocytes (PubMed:25597510). {ECO:0000269|PubMed:25597510, ECO:0000269|PubMed:25597511}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs200032855 rs777313457 rs7938203 rs144078282 rs786205137 rs886041118 rs748915609 rs150857620 rs748010262 rs786205138 rs759500860 rs886041120 |
| Subcellular location [CC] | Mitochondrion intermembrane space {ECO:0000269|PubMed:25597510, ECO:0000269|PubMed:31522117, ECO:0000269|PubMed:34115842}. |
| Mouse PG classification | NA |
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