| Gene Information | |
|---|---|
| Gene Name | CLP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000172409 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94992 |
| Gene Card | HEXIM1 |
| Uniprot ID | O94992 |
| Pfam | PF15313 |
| In ASD | no |
| Allosteric Prediction | no (-0.790004009) |
| Ortholog in Animals | Alpaca_ CLP1 ( ortholog_one2one ) Dog_ CLP1 ( ortholog_one2one ) GuineaPig_ CLP1 ( ortholog_one2one ) Macaque_ CLP1 ( ortholog_one2one ) Mouse_ Clp1 ( ortholog_one2one ) Pig_ CLP1 ( ortholog_one2one ) Rat_ Clp1 ( ortholog_one2one ) Rabbit_ CLP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NOL9 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues. {ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:15713661}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001445(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2GD7 (NMR - ) 3S9G (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12581153, ECO:0000269|PubMed:12832472, ECO:0000269|PubMed:12941847, ECO:0000269|PubMed:16362050, ECO:0000269|PubMed:17395637}. Cytoplasm {ECO:0000269|PubMed:12581153, ECO:0000269|PubMed:17395637}. Note=Binds alpha-importin and is mostly nuclear (PubMed:16362050). |
| Mouse PG classification | NA |
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