| Gene Information | |
|---|---|
| Gene Name | CLDN23 |
| Organism | Homo sapiens (Human) |
| Gene Length | 292 |
| Protein Names | Claudin-23 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000253958 ) 3 ( ENSG00000285098 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96B33 |
| Gene Card | CLDN23 |
| Uniprot ID | Q96B33 |
| Pfam | PF00822 |
| In ASD | no |
| Allosteric Prediction | no (-1.114683083) |
| Ortholog in Animals | Alpaca_ CLDN23 ( ortholog_one2one ) Macaque_ CLDN23 ( ortholog_one2one ) Mouse_ Cldn23 ( ortholog_one2one ) Pig_ CLDN23 ( ortholog_one2one ) Rat_ Cldn23 ( ortholog_one2one ) Rabbit_ CLDN23 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CLDN1, CLDN5, CLDN8, CLDN3, CLDN20, CLDN11, CLDN14, CLDN18, CLDN7, CLDN10, CLDN9, CLDN17, CLDN24, CLDN22, CLDN4, CLDN15, CLDN19, CLDN34, CLDN2, CLDN25, CLDN16, CLDN6 |
| Tissue | colon, stomach |
| Tissue Specificity | Expressed in germinal center B-cells, placenta, stomach as well as in colon tumor. {ECO:0000269|PubMed:12736707}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12548737 |
| Subcellular location [CC] | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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