Gene Information
Gene NamePRSS14
OrganismHomo sapiens (Human)
Gene Length855
Protein NamesSuppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9Y5Y6
Gene CardST14
Uniprot IDQ9Y5Y6
PfamPF00431; PF00057; PF01390; PF00089
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1EAW  (X-ray  2.93A  1EAX  (X-ray  1.30A  2GV6  (X-ray  2.10A  2GV7  (X-ray  2.20A  3BN9  (X-ray  2.17A  3NCL  (X-ray  1.19A  3NPS  (X-ray  1.50A  3P8F  (X-ray  2.00A  3P8G  (X-ray  1.20A  3SO3  (X-ray  2.10A  4IS5  (X-ray  1.48A  4ISL  (X-ray  2.29A  4ISN  (X-ray  2.45A  4ISO  (X-ray  2.01A  4JYT  (X-ray  2.00A  4JZ1  (X-ray  1.90A  4JZI  (X-ray  2.00A  4O97  (X-ray  2.20A  4O9V  (X-ray  1.90A  4R0I  (X-ray  1.90A  5LYO  (X-ray  2.50A  6N4T  (X-ray  1.95A  6T9T  (X-ray  1.69A 
DBSNP rs7126904  rs17667603  rs137852931 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type II membrane protein {ECO:0000305}.
Mouse PG classificationNA
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