| Gene Information | |
|---|---|
| Gene Name | NLRP8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1048 |
| Protein Names | NACHT, LRR and PYD domains-containing protein 8 (Nucleotide-binding oligomerization domain protein 16) (PYRIN and NACHT-containing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000179709 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86W28 |
| Gene Card | NLRP8 |
| Uniprot ID | Q86W28 |
| Pfam | PF13516; PF05729; PF17776; PF17779; PF02758 |
| In ASD | no |
| Allosteric Prediction | no (-1.022582861) |
| Ortholog in Animals | Alpaca_ NLRP8 ( ortholog_one2one ) Dog_ NLRP8 ( ortholog_one2one ) Macaque_ NLRP8 ( ortholog_one2one ) Pig_ NLRP8 ( ortholog_one2one ) Rabbit_ NLRP8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NLRP9, NLRC5, NLRP14, NLRP7, NLRP4, CIITA, NOD1, NLRP10, NLRP3, NLRP5, NLRP6, NLRP11, NLRP2, PYDC2, NLRC3, NLRX1, NLRP12, NLRP13, NLRP1, NOD2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs306507 rs306506 rs61739987 rs11880691 rs7259764 rs11880748 rs41391053 rs41481648 rs306496 rs306481 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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