| Gene Information | |
|---|---|
| Gene Name | PIWIL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 973 |
| Protein Names | Piwi-like protein 2 (EC 3.1.26.-) (Cancer/testis antigen 80) (CT80) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000197181 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TC59 |
| Gene Card | PIWIL2 |
| Uniprot ID | Q8TC59 |
| Pfam | PF08699; PF02170; PF02171 |
| In ASD | no |
| Allosteric Prediction | no (-0.544069092) |
| Ortholog in Animals | Alpaca_ PIWIL2 ( ortholog_one2one ) Dog_ PIWIL2 ( ortholog_one2one ) GuineaPig_ PIWIL2 ( ortholog_one2one ) Macaque_ PIWIL2 ( ortholog_one2one ) Mouse_ Piwil2 ( ortholog_one2one ) Pig_ PIWIL2 ( ortholog_one2one ) Rat_ Piwil2 ( ortholog_one2one ) Rabbit_ PIWIL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PIWIL1, PIWIL4, PIWIL3 |
| Tissue | duodenum, testis |
| Tissue Specificity | Expressed in adult testis and in most tumors. {ECO:0000269|PubMed:16377660}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.025000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3O7X (X-ray 2.92A ) 3QIR (X-ray 2.45A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q8CDG1}. Note=Present in chromatoid body. Probable component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250|UniProtKB:Q8CDG1}. |
| Mouse PG classification | NA |
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