| Gene Information | |
|---|---|
| Gene Name | CLECSF8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 215 |
| Protein Names | C-type lectin domain family 4 member D (C-type lectin superfamily member 8) (C-type lectin-like receptor 6) (CLEC-6) (Dendritic cell-associated C-type lectin 3) (DC-associated C-type lectin 3) (Dectin-3) (CD antigen CD368) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8WXI8 |
| Gene Card | CLEC4D |
| Uniprot ID | Q8WXI8 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression is confined mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma. {ECO:0000269|PubMed:14971047}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LS8 (NMR - ) 3WHD (X-ray 2.29A ) |
| DBSNP | rs4304840 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:23911656}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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