Gene Information
Gene NameCLEC13B
OrganismHomo sapiens (Human)
Gene Length1722
Protein NamesLymphocyte antigen 75 (Ly-75) (C-type lectin domain family 13 member B) (DEC-205) (gp200-MR6) (CD antigen CD205)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO60449
Gene CardLY75
Uniprot IDO60449
PfamPF00040; PF00059
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. {ECO:0000269|PubMed:12824192, ECO:0000269|PubMed:9862343}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7JPT  (EM  3.20A  7JPU  (EM  5.00A 
DBSNP rs35284483  rs2271381  rs2729709  rs34020639  rs1397706  rs3951216  rs3815875  rs2303549  rs12692566  rs17827158  rs2059696  rs35941588 
Subcellular location [CC]Membrane {ECO:0000250};
Single-pass type I membrane protein {ECO:0000250}.
Mouse PG classificationNA
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