| Gene Information | |
|---|---|
| Gene Name | ABAT |
| Organism | Homo sapiens (Human) |
| Gene Length | 500 |
| Protein Names | 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT) |
| Target Name | 4-aminobutyrate aminotransferase, mitochondrial |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000183044 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P80404 |
| Gene Card | ABAT |
| Uniprot ID | P80404 |
| Pfam | PF00202 |
| In ASD | yes |
| Allosteric Prediction | yes (1.392777585) |
| Ortholog in Animals | Alpaca_ ABAT ( ortholog_one2one ) Dog_ ABAT ( ortholog_one2one ) GuineaPig_ ABAT ( ortholog_one2one ) Macaque_ ABAT ( ortholog_one2one ) Mouse_ Abat ( ortholog_one2one ) Pig_ ABAT ( ortholog_one2one ) Rat_ Abat ( ortholog_one2one ) Rabbit_ ABAT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PHYKPL, OAT, ETNPPL, AGXT2 |
| Tissue | NA |
| Tissue Specificity | Liver > pancreas > brain > kidney > heart > placenta. {ECO:0000269|PubMed:7851425}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.007731(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1731017 rs121434578 |
| Subcellular location [CC] | Mitochondrion matrix. |
| Mouse PG classification | NA |
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