| Gene Information | |
|---|---|
| Gene Name | CLDN3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 220 |
| Protein Names | Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000165215 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O15551 |
| Gene Card | CLDN3 |
| Uniprot ID | O15551 |
| Pfam | PF00822 |
| In ASD | no |
| Allosteric Prediction | no (-0.371443098) |
| Ortholog in Animals | Alpaca_ CLDN3 ( ortholog_one2many ) Dog_ CLDN3 ( ortholog_one2one ) GuineaPig_ CLDN3 ( ortholog_one2one ) Macaque_ CLDN3 ( ortholog_one2one ) Mouse_ Cldn3 ( ortholog_one2one ) Rat_ Cldn3 ( ortholog_one2one ) |
| Ohnologs | CLDN15, CLDN20 |
| Paralogs | CLDN1, CLDN5, CLDN8, CLDN20, CLDN11, CLDN14, CLDN18, CLDN7, CLDN10, CLDN9, CLDN17, CLDN24, CLDN22, CLDN23, CLDN4, CLDN15, CLDN19, CLDN34, CLDN2, CLDN25, CLDN16, CLDN6 |
| Tissue | colon, pancreas, seminal.vesicle, submandibular.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell junction, tight junction {ECO:0000250|UniProtKB:Q9Z0G9}. Cell membrane {ECO:0000250|UniProtKB:Q9Z0G9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Z0G9}. |
| Mouse PG classification | NA |
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