| Gene Information | |
|---|---|
| Gene Name | RASL11A |
| Organism | Homo sapiens (Human) |
| Gene Length | 242 |
| Protein Names | Ras-like protein family member 11A (EC 3.6.5.2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000122035 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6T310 |
| Gene Card | RASL11A |
| Uniprot ID | Q6T310 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-1.924591915) |
| Ortholog in Animals | Alpaca_ RASL11A ( ortholog_one2one ) Dog_ RASL11A ( ortholog_one2one ) GuineaPig_ RASL11A ( ortholog_one2one ) Macaque_ RASL11A ( ortholog_one2one ) Mouse_ Rasl11a ( ortholog_one2one ) Pig_ RASL11A ( ortholog_one2one ) Rat_ Rasl11a ( ortholog_one2one ) Rabbit_ RASL11A ( ortholog_one2one ) |
| Ohnologs | RASL11B |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RRAS2, RAP2B, HRAS, RERG, RASL12, RRAD, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, MRAS, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, REM2, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells. {ECO:0000269|PubMed:15033445, ECO:0000269|PubMed:17628721}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000250}. Note=Associates with rDNA transcription unit throughout the cell cycle. {ECO:0000250}. |
| Mouse PG classification | NA |
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