| Gene Information | |
|---|---|
| Gene Name | CLDN16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 235 |
| Protein Names | Claudin-16 (Paracellin-1) (PCLN-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000113946 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9Y5I7 |
| Gene Card | CLDN16 |
| Uniprot ID | Q9Y5I7 |
| Pfam | PF00822 |
| In ASD | no |
| Allosteric Prediction | no (-0.448889261) |
| Ortholog in Animals | Alpaca_ CLDN16 ( ortholog_one2one ) Dog_ CLDN16 ( ortholog_one2one ) GuineaPig_ CLDN16 ( ortholog_one2one ) Macaque_ CLDN16 ( ortholog_one2one ) Mouse_ Cldn16 ( ortholog_one2one ) Pig_ CLDN16 ( ortholog_one2one ) Rat_ Cldn16 ( ortholog_one2one ) Rabbit_ CLDN16 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CLDN1, CLDN5, CLDN8, CLDN3, CLDN20, CLDN11, CLDN14, CLDN18, CLDN7, CLDN10, CLDN9, CLDN17, CLDN24, CLDN22, CLDN23, CLDN4, CLDN15, CLDN19, CLDN34, CLDN2, CLDN25, CLDN6 |
| Tissue | kidney |
| Tissue Specificity | Kidney-specific, including the thick ascending limb of Henle (TAL). |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs104893731 rs968906940 rs104893729 rs104893730 rs104893725 rs104893722 rs104893723 rs1270704258 rs104893726 rs104893727 rs104893728 rs104893721 |
| Subcellular location [CC] | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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