Gene Information
Gene NameCLDN15
OrganismHomo sapiens (Human)
Gene Length228
Protein NamesClaudin-15
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000106404 )
Evolutionary StageEumetazoa
AlphaFoldDBP56746
Gene CardCLDN15
Uniprot IDP56746
PfamPF00822
In ASDno
Allosteric Predictionno (-1.527464895)
Ortholog in AnimalsAlpaca_ CLDN15 ( ortholog_one2many )
Dog_ CLDN15 ( ortholog_one2one )
GuineaPig_ CLDN15 ( ortholog_one2one )
Macaque_ CLDN15 ( ortholog_one2one )
Mouse_ Cldn15 ( ortholog_one2one )
Pig_ CLDN15 ( ortholog_one2one )
Rat_ Cldn15 ( ortholog_one2one )
Rabbit_ CLDN15 ( ortholog_one2one )
OhnologsCLDN3, CLDN2, CLDN4, CLDN1, CLDN19
ParalogsCLDN1, CLDN5, CLDN8, CLDN3, CLDN20, CLDN11, CLDN14, CLDN18, CLDN7, CLDN10, CLDN9, CLDN17, CLDN24, CLDN22, CLDN23, CLDN4, CLDN19, CLDN34, CLDN2, CLDN25, CLDN16, CLDN6
Tissuesmall.intestine
Tissue SpecificityDetected in colon (at protein level). {ECO:0000269|PubMed:12055082}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell junction, tight junction. Cell membrane;
Multi-pass membrane protein. Note=Tight junctions form continuous circumferential cell-cell contacts at the borders of apical and lateral cell membranes that seal the intercellular space and show up as strand-like structures in electron microscopy.
Mouse PG classificationNA
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