| Gene Information | |
|---|---|
| Gene Name | CCDC57 |
| Organism | Homo sapiens (Human) |
| Gene Length | 915 |
| Protein Names | Coiled-coil domain-containing protein 57 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000176155 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q2TAC2 |
| Gene Card | CCDC57 |
| Uniprot ID | Q2TAC2 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.250446662) |
| Ortholog in Animals | Alpaca_ CCDC57 ( ortholog_one2one ) Dog_ CCDC57 ( ortholog_one2one ) GuineaPig_ CCDC57 ( ortholog_one2one ) Macaque_ CCDC57 ( ortholog_one2one ) Mouse_ Ccdc57 ( ortholog_one2one ) Pig_ CCDC57 ( ortholog_one2one ) Rat_ Ccdc57 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CCHCR1, CIP2A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34543170 rs7406116 rs7209474 rs4625783 rs7406163 rs7406162 rs7213172 rs11077969 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:32402286}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:32402286}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:32402286}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:32402286}. Note=Localizes to resolvable rings at the proximal end of centrioles (PubMed:32402286). In mitotic cells, localizes to spindle microtubules during metaphase (PubMed:32402286). {ECO:0000269|PubMed:32402286}. |
| Mouse PG classification | NA |
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