| Gene Information | |
|---|---|
| Gene Name | CIR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 450 |
| Protein Names | Corepressor interacting with RBPJ 1 (CBF1-interacting corepressor) (Recepin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000138433 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86X95 |
| Gene Card | CIR1 |
| Uniprot ID | Q86X95 |
| Pfam | PF10197 |
| In ASD | no |
| Allosteric Prediction | no (-1.104172396) |
| Ortholog in Animals | Alpaca_ CIR1 ( ortholog_one2one ) Dog_ CIR1 ( ortholog_one2one ) GuineaPig_ CIR1 ( ortholog_one2one ) Macaque_ CIR1 ( ortholog_one2one ) Mouse_ Cir1 ( ortholog_one2one ) Pig_ CIR1 ( ortholog_one2one ) Rat_ Cir1 ( ortholog_one2one ) Rabbit_ CIR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, brain, placenta, liver, skeletal muscle and pancreas. {ECO:0000269|PubMed:9874765}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001790(Rat);0.115385(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ZYM (EM 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Colocalizes with NEK6 in the centrosome. |
| Mouse PG classification | NA |
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