| Gene Information | |
|---|---|
| Gene Name | KHSRP |
| Organism | Homo sapiens (Human) |
| Gene Length | 711 |
| Protein Names | Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75) |
| Target Name | far upstream element-binding protein 2 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000088247 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92945 |
| Gene Card | KHSRP |
| Uniprot ID | Q92945 |
| Pfam | PF09005; PF00013 |
| In ASD | no |
| Allosteric Prediction | yes (0.68390961) |
| Ortholog in Animals | Alpaca_ KHSRP ( ortholog_one2one ) Dog_ KHSRP ( ortholog_one2one ) GuineaPig_ KHSRP ( ortholog_one2one ) Macaque_ KHSRP ( ortholog_one2one ) Mouse_ Khsrp ( ortholog_one2one ) Pig_ KHSRP ( ortholog_one2one ) Rat_ Khsrp ( ortholog_one2one ) |
| Ohnologs | FUBP3, FUBP1 |
| Paralogs | HNRNPK, NOVA2, FUBP3, FUBP1, IGF2BP1, PCBP4, PCBP3, PCBP1, IGF2BP3, IGF2BP2, NOVA1, PCBP2 |
| Tissue | NA |
| Tissue Specificity | Detected in neural and non-neural cell lines. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.014286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2HH2 (NMR - ) 2HH3 (NMR - ) 2JVZ (NMR - ) 2OPU (NMR - ) 2OPV (NMR - ) 4B8T (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19198587}. Cytoplasm {ECO:0000269|PubMed:19198587}. Note=A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites. {ECO:0000250}. |
| Mouse PG classification | NA |
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