Gene Information
Gene NameCIDEC
OrganismHomo sapiens (Human)
Gene Length238
Protein NamesCell death activator CIDE-3 (Cell death-inducing DFFA-like effector protein C) (Fat-specific protein FSP27 homolog)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000187288 )
Evolutionary StageVertebrata
AlphaFoldDBQ96AQ7
Gene CardCIDEC
Uniprot IDQ96AQ7
PfamPF02017
In ASDno
Allosteric Predictionno (-1.000821773)
Ortholog in AnimalsAlpaca_ CIDEC ( ortholog_one2one )
Dog_ CIDEC ( ortholog_one2one )
GuineaPig_ CIDEC ( ortholog_one2one )
Macaque_ CIDEC ( ortholog_one2one )
Mouse_ Cidec ( ortholog_one2one )
Pig_ CIDEC ( ortholog_one2one )
Rat_ Cidec ( ortholog_one2one )
Rabbit_ CIDEC ( ortholog_one2one )
OhnologsNA
ParalogsCIDEA, CIDEB, DFFA
Tissueadipose.tissue, breast, greater.omentum, subcutaneous.adipose.tissue
Tissue SpecificityExpressed mainly in adipose tissue, small intestine, heart, colon and stomach and, at lower levels, in brain, kidney and liver. {ECO:0000269|PubMed:12429024, ECO:0000269|PubMed:18334488}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000250}. Endoplasmic reticulum. Lipid droplet. Note=Diffuses quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby enabling its rapid enrichment at lipid droplet contact sites.
Mouse PG classificationNA
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