| Gene Information | |
|---|---|
| Gene Name | CIBAR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 289 |
| Protein Names | CBY1-interacting BAR domain-containing protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000188343 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | A1XBS5 |
| Gene Card | CIBAR1 |
| Uniprot ID | A1XBS5 |
| Pfam | PF06730 |
| In ASD | no |
| Allosteric Prediction | no (-1.633807689) |
| Ortholog in Animals | Alpaca_ CIBAR1 ( ortholog_one2one ) Dog_ CIBAR1 ( ortholog_one2one ) GuineaPig_ CIBAR1 ( ortholog_one2one ) Macaque_ CIBAR1 ( ortholog_one2one ) Mouse_ Cibar1 ( ortholog_one2one ) Rat_ Cibar1 ( ortholog_one2one ) Rabbit_ CIBAR1 ( ortholog_one2one ) |
| Ohnologs | CIBAR2 |
| Paralogs | CIBAR2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs36117362 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:27528616, ECO:0000269|PubMed:30404948}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:27528616}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:27528616, ECO:0000269|PubMed:30395363}. Cell projection, cilium {ECO:0000250|UniProtKB:Q8BP22}. Nucleus {ECO:0000269|PubMed:30404948}. Mitochondrion inner membrane {ECO:0000269|PubMed:30404948}; Peripheral membrane protein {ECO:0000269|PubMed:30404948}; Matrix side {ECO:0000269|PubMed:30404948}. Note=Weak punctate vesicular distribution throughout the cytoplasm (PubMed:27528616). Localizes at the distal end of mother centrioles (PubMed:27528616). Extensive colocalization with CBY1 at mother centrioles (PubMed:27528616). {ECO:0000269|PubMed:27528616}.; [Isoform 3]: Nucleus {ECO:0000269|PubMed:17646714}. |
| Mouse PG classification | NA |
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