| Gene Information | |
|---|---|
| Gene Name | HYRC |
| Organism | Homo sapiens (Human) |
| Gene Length | 4128 |
| Protein Names | DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | PRKDC |
| Uniprot ID | P78527 |
| Pfam | PF20500; PF20502; PF08163; PF19704; PF02259; PF02260; PF00454 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001459(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5LUQ (X-ray 4.30A ) 5W1R (EM 4.40A ) 5Y3R (EM 6.60A ) 6ZFP (EM 3.24A ) 6ZH2 (EM 3.92A ) 6ZH4 (EM 3.62A ) 6ZH6 (EM 3.93A ) 6ZH8 (EM 4.14A ) 6ZHA (EM 3.91A ) 6ZHE (EM 7.24A ) 7K0Y (EM 3.70A ) 7K10 (EM 3.30A ) 7K11 (EM 3.21A ) 7K19 (EM 4.30A ) 7K1B (EM 4.30A ) 7K1J (EM 3.90A ) 7K1K (EM 4.10A ) 7K1N (EM 3.90A ) 7LT3 (EM 4.60A ) 7NFC (EM 4.14A ) 7NFE (EM 4.29A ) 7OTM (EM 3.33A ) 7OTP (EM 3.40A ) 7OTV (EM 3.24A ) 7OTW (EM 2.99A ) 7OTY (EM 2.96A ) 7SGL (EM 3.00A ) 7SU3 (EM 3.30A ) 7SUD (EM 3.60A ) 7TYR (EM 3.33A ) |
| DBSNP | rs8177999 rs758032015 rs8178017 rs55925466 rs8178033 rs55811715 rs8178040 rs8178046 rs8178070 rs781401034 rs34598508 rs191531119 rs8178090 rs8178104 rs8178106 rs56182356 rs55735910 rs56042895 rs8178147 rs55923149 rs8178178 rs4278157 rs587777685 rs56135402 rs8178208 rs55793951 rs8178216 rs8178225 rs7830743 rs8178228 rs8178232 rs587777686 rs55866966 rs8178236 rs56216442 rs8178245 rs8178248 rs55670423 rs56090750 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12231622, ECO:0000269|PubMed:14734805, ECO:0000269|PubMed:22002106}. Nucleus, nucleolus {ECO:0000269|PubMed:22002106, ECO:0000269|PubMed:32103174}. |
| Mouse PG classification | NA |
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