| Gene Information | |
|---|---|
| Gene Name | E2F6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 281 |
| Protein Names | Transcription factor E2F6 (E2F-6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000169016 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75461 |
| Gene Card | E2F6 |
| Uniprot ID | O75461 |
| Pfam | PF16421; PF02319 |
| In ASD | no |
| Allosteric Prediction | no (-0.369114301) |
| Ortholog in Animals | Alpaca_ E2F6 ( ortholog_one2one ) Dog_ E2F6 ( ortholog_one2one ) GuineaPig_ E2F6 ( ortholog_one2one ) Macaque_ E2F6 ( ortholog_one2one ) Mouse_ E2f6 ( ortholog_one2one ) Pig_ E2F6 ( ortholog_one2one ) Rat_ E2f6 ( ortholog_one2one ) Rabbit_ E2F6 ( ortholog_one2one ) |
| Ohnologs | E2F1, E2F3, E2F2 |
| Paralogs | E2F5, E2F2, E2F3, E2F8, E2F1, E2F4, E2F7 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen. {ECO:0000269|PubMed:9689056}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9689056, ECO:0000269|PubMed:9704927}. |
| Mouse PG classification | NA |
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