| Gene Information | |
|---|---|
| Gene Name | CIAO2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 163 |
| Protein Names | Cytosolic iron-sulfur assembly component 2B (MSS19-interacting protein of 18 kDa) (Mitotic spindle-associated MMXD complex subunit MIP18) (Protein FAM96B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000166595 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y3D0 |
| Gene Card | CIAO2B |
| Uniprot ID | Q9Y3D0 |
| Pfam | PF01883 |
| In ASD | no |
| Allosteric Prediction | no (-1.410234573) |
| Ortholog in Animals | Alpaca_ CIAO2B ( ortholog_one2one ) Dog_ CIAO2B ( ortholog_one2one ) GuineaPig_ CIAO2B ( ortholog_one2one ) Macaque_ CIAO2B ( ortholog_one2one ) Mouse_ Ciao2b ( ortholog_one2one ) Pig_ CIAO2B ( ortholog_one2one ) Rat_ Ciao2b ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CIAO2A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002240(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:20797633}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:20797633, ECO:0000269|PubMed:29848660}. Midbody {ECO:0000269|PubMed:29848660}. Note=In mitosis, localizes to the spindle during metaphase and the spindle midbody during telophase (PubMed:29848660). Co-localizes with KIF4A to the spindle midzone and midbody during telophase and cytokinesis (PubMed:29848660). {ECO:0000269|PubMed:29848660}. |
| Mouse PG classification | NA |
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