| Gene Information | |
|---|---|
| Gene Name | CHTOP |
| Organism | Homo sapiens (Human) |
| Gene Length | 248 |
| Protein Names | Chromatin target of PRMT1 protein (Friend of PRMT1 protein) (Small arginine- and glycine-rich protein) (SRAG) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000160679 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y3Y2 |
| Gene Card | CHTOP |
| Uniprot ID | Q9Y3Y2 |
| Pfam | PF13865 |
| In ASD | no |
| Allosteric Prediction | no (-1.011154772) |
| Ortholog in Animals | Alpaca_ CHTOP ( ortholog_one2one ) Dog_ CHTOP ( ortholog_one2one ) GuineaPig_ CHTOP ( ortholog_one2one ) Macaque_ CHTOP ( ortholog_one2one ) Mouse_ Chtop ( ortholog_one2one ) Pig_ CHTOP ( ortholog_one2one ) Rat_ Chtopl1 ( ortholog_one2many ) Rat_ Chtop ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | ALYREF, POLDIP3 |
| Tissue | NA |
| Tissue Specificity | Expressed in an erythroid progenitor cell line derived from peripheral blood. Expressed in glioblastoma cells (PubMed:25284789). {ECO:0000269|PubMed:20688955, ECO:0000269|PubMed:25284789}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.015385(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19254951}. Nucleus, nucleolus {ECO:0000269|PubMed:19254951}. Nucleus, nucleoplasm {ECO:0000269|PubMed:23826332}. Nucleus speckle {ECO:0000269|PubMed:23299939, ECO:0000269|PubMed:23826332}. Note=Mostly associated with facultative heterochromatin (By similarity). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur (PubMed:23826332). {ECO:0000250|UniProtKB:Q9CY57, ECO:0000269|PubMed:23826332}. |
| Mouse PG classification | NA |
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