| Gene Information | |
|---|---|
| Gene Name | CHST8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 424 |
| Protein Names | Carbohydrate sulfotransferase 8 (EC 2.8.2.-) (GalNAc-4-O-sulfotransferase 1) (GalNAc-4-ST1) (GalNAc4ST-1) (N-acetylgalactosamine-4-O-sulfotransferase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000124302 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H2A9 |
| Gene Card | CHST8 |
| Uniprot ID | Q9H2A9 |
| Pfam | PF03567 |
| In ASD | no |
| Allosteric Prediction | no (-1.155175109) |
| Ortholog in Animals | Alpaca_ CHST8 ( ortholog_one2one ) Dog_ CHST8 ( ortholog_one2one ) GuineaPig_ CHST8 ( ortholog_one2one ) Macaque_ CHST8 ( ortholog_one2one ) Mouse_ Chst8 ( ortholog_one2one ) Pig_ CHST8 ( ortholog_one2one ) Rabbit_ CHST8 ( ortholog_one2one ) |
| Ohnologs | CHST9, CHST13 |
| Paralogs | CHST11, CHST14, CHST10, CHST12, CHST13, CHST9 |
| Tissue | pituitary.gland |
| Tissue Specificity | Predominantly expressed in pituitary gland. In brain, it is expressed in pituitary gland, cerebellum, medulla oblongata, pons, thalamus and spinal cord. Expressed in the epidermis. Expressed at lower level in lung, spleen, adrenal gland, placenta, prostate, testis, mammary gland and trachea. {ECO:0000269|PubMed:10988300, ECO:0000269|PubMed:11001942, ECO:0000269|PubMed:11445554, ECO:0000269|PubMed:22289416}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs149660944 rs1261984908 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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