| Gene Information | |
|---|---|
| Gene Name | CALCR |
| Organism | Homo sapiens (Human) |
| Gene Length | 474 |
| Protein Names | Calcitonin receptor (CT-R) |
| Target Name | calcitonin receptor |
| Target Type | Successful target |
| Gene Age | 950 ( ENSG00000004948 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P30988 |
| Gene Card | CALCR |
| Uniprot ID | P30988 |
| Pfam | PF00002; PF02793 |
| In ASD | no |
| Allosteric Prediction | yes (1.555628951) |
| Ortholog in Animals | Alpaca_ CALCR ( ortholog_one2one ) Dog_ CALCR ( ortholog_one2one ) GuineaPig_ CALCR ( ortholog_one2one ) Macaque_ CALCR ( ortholog_one2one ) Mouse_ Calcr ( ortholog_one2one ) Pig_ CALCR ( ortholog_one2one ) Rat_ Calcr ( ortholog_one2one ) Rabbit_ CALCR ( ortholog_one2one ) |
| Ohnologs | CALCRL, GLP1R, PTH2R |
| Paralogs | ADGRE3, ADGRL2, VIPR1, ADGRL4, ADGRE2, ADGRG4, ADGRD1, ADGRL3, GHRHR, PTH2R, ADGRE1, ADGRD2, ADGRL1, ADGRB3, EVA1C, ADGRG1, SCTR, ADGRF5, ADGRA3, GLP2R, PTH1R, ADGRF3, GIPR, ADGRA1, ADGRF1, ADCYAP1R1, ADGRG5, ADGRE5, CRHR2, ADGRB2, ADGRG6, GCGR, ADGRB1, ADGRG2, ADGRA2, ADGRF4, VIPR2, ADGRG7, CALCRL, ADGRG3, CRHR1, GLP1R |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5II0 (X-ray 2.10A ) 5UZ7 (EM 4.10A ) 6NIY (EM 3.34A ) 6PFO (X-ray 1.78A ) 6PGQ (X-ray 2.85A ) 7TYF (EM 2.20A ) 7TYH (EM 3.30A ) 7TYI (EM 3.30A ) 7TYL (EM 3.30A ) 7TYN (EM 2.60A ) 7TYO (EM 2.70A ) 7TYW (EM 3.00A ) 7TYX (EM 2.55A ) 7TYY (EM 3.00A ) 7TZF (EM 2.40A ) |
| DBSNP | rs1801197 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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