| Gene Information | |
|---|---|
| Gene Name | CHPT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 406 |
| Protein Names | Cholinephosphotransferase 1 (hCPT1) (EC 2.7.8.2) (AAPT1-like protein) (Diacylglycerol cholinephosphotransferase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000111666 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WUD6 |
| Gene Card | CHPT1 |
| Uniprot ID | Q8WUD6 |
| Pfam | PF01066 |
| In ASD | no |
| Allosteric Prediction | no (-0.32324454) |
| Ortholog in Animals | Alpaca_ CHPT1 ( ortholog_one2one ) Dog_ CHPT1 ( ortholog_one2one ) GuineaPig_ CHPT1 ( ortholog_one2one ) Macaque_ CHPT1 ( ortholog_one2one ) Mouse_ Chpt1 ( ortholog_one2one ) Pig_ CHPT1 ( ortholog_one2one ) Rat_ Chpt1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CEPT1, SELENOI |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis, colon, small intestine, heart, prostate and spleen. Also detected in kidney, skeletal muscle, pancreas, leukocytes, ovary and thymus. Weakly expressed in the brain, placenta and lung. Overexpressed in cancerous breast epithelial cell lines. {ECO:0000269|PubMed:10893425, ECO:0000269|PubMed:12359261}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3205421 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:12221122}; Multi-pass membrane protein {ECO:0000269|PubMed:12221122}. |
| Mouse PG classification | NA |
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