| Gene Information | |
|---|---|
| Gene Name | SLC28A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 691 |
| Protein Names | Solute carrier family 28 member 3 (Concentrative Na(+)-nucleoside cotransporter 3) (CNT 3) (hCNT3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000197506 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9HAS3 |
| Gene Card | SLC28A3 |
| Uniprot ID | Q9HAS3 |
| Pfam | PF07670; PF07662; PF01773 |
| In ASD | no |
| Allosteric Prediction | no (-0.332917404) |
| Ortholog in Animals | Alpaca_ SLC28A3 ( ortholog_one2one ) Dog_ SLC28A3 ( ortholog_one2one ) GuineaPig_ SLC28A3 ( ortholog_one2one ) Macaque_ SLC28A3 ( ortholog_one2one ) Mouse_ Slc28a3 ( ortholog_one2one ) Pig_ SLC28A3 ( ortholog_one2one ) Rat_ Slc28a3 ( ortholog_one2one ) Rabbit_ SLC28A3 ( ortholog_one2one ) |
| Ohnologs | SLC28A2, SLC28A1 |
| Paralogs | SLC28A2, SLC28A1 |
| Tissue | NA |
| Tissue Specificity | Expressed in pancreas, bone marrow, trachea, mammary gland, liver, prostate, and regions of intestine, brain, lung, placenta, testis, kidney, and heart. {ECO:0000269|PubMed:11032837}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 6KSW (EM 3.60A ) |
| DBSNP | rs11568401 rs11568403 rs45621433 rs11568411 rs10868138 rs11140503 rs11568418 rs45525131 rs140138960 rs11568388 rs11568405 rs56350726 rs11568398 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:21998139}; Multi-pass membrane protein {ECO:0000269|PubMed:32776918}.; [Isoform 2]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18827020}; Multi-pass membrane protein {ECO:0000269|PubMed:32776918}. |
| Mouse PG classification | NA |
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