| Gene Information | |
|---|---|
| Gene Name | TBC1D24 |
| Organism | Homo sapiens (Human) |
| Gene Length | 559 |
| Protein Names | TBC1 domain family member 24 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000162065 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9ULP9 |
| Gene Card | TBC1D24 |
| Uniprot ID | Q9ULP9 |
| Pfam | PF00566; PF07534 |
| In ASD | no |
| Allosteric Prediction | no (-1.000138477) |
| Ortholog in Animals | Alpaca_ TBC1D24 ( ortholog_one2one ) Dog_ TBC1D24 ( ortholog_one2one ) GuineaPig_ TBC1D24 ( ortholog_one2one ) Macaque_ TBC1D24 ( ortholog_one2one ) Mouse_ Tbc1d24 ( ortholog_one2one ) Pig_ TBC1D24 ( ortholog_one2one ) Rat_ Tbc1d24 ( ortholog_one2one ) Rabbit_ TBC1D24 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression in brain. {ECO:0000269|PubMed:20727515}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs201257588 rs398122966 rs587777147 rs747821285 rs770820144 rs267607103 rs863223337 rs483352866 rs763670146 rs397514713 rs398122965 rs267607104 rs199700840 rs72768728 rs797044548 rs765965968 rs564477999 rs1596973014 rs1251822607 rs267607105 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:20727515}; Peripheral membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:20727515}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9VIH7}. Presynapse {ECO:0000269|PubMed:31257402}. Note=Mainly cytoplasmatic with partial expression at the plasma membrane (PubMed:20727515). Associates with certain types of membrane phosphoinositides, preferentially those phosphorylated at the D5 position of the inositol ring such as phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3) (By similarity). {ECO:0000250|UniProtKB:Q9VIH7, ECO:0000269|PubMed:20727515}. |
| Mouse PG classification | NA |
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