| Gene Information | |
|---|---|
| Gene Name | LMOD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 560 |
| Protein Names | Leiomodin-3 (Leiomodin, fetal form) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000163380 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q0VAK6 |
| Gene Card | LMOD3 |
| Uniprot ID | Q0VAK6 |
| Pfam | PF03250 |
| In ASD | no |
| Allosteric Prediction | no (-0.995798115) |
| Ortholog in Animals | Alpaca_ LMOD3 ( ortholog_one2one ) Dog_ LMOD3 ( ortholog_one2one ) GuineaPig_ LMOD3 ( ortholog_one2one ) Macaque_ LMOD3 ( ortholog_one2one ) Mouse_ Lmod3 ( ortholog_one2one ) Pig_ LMOD3 ( ortholog_one2one ) Rat_ Lmod3 ( ortholog_one2one ) Rabbit_ LMOD3 ( ortholog_one2one ) |
| Ohnologs | LMOD1 |
| Paralogs | TMOD1, LMOD1, TMOD2, LMOD2, TMOD3, TMOD4 |
| Tissue | heart, skeletal.muscle, artery, pulmonary.valve, tongue |
| Tissue Specificity | Expressed in cardiac and at higher levels in skeletal muscles (at protein level). {ECO:0000269|PubMed:25250574}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35740823 rs9835034 rs6810145 rs17005363 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:25250574}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000269|PubMed:25250574}. Cytoplasm, myofibril, sarcomere, A band {ECO:0000250|UniProtKB:E9QA62}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:25250574}. Note=Highly expressed in nonstriated areas of developing myotubes, where it shows a granular cytoplasmic pattern. In sarcomeres, highly expressed in the M band region and, at lower levels, along actin thin filaments. Not detected in Z-disks. In sarcomeres, may be located near, but not at, actin thin filament pointed end. {ECO:0000269|PubMed:25250574}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |