| Gene Information | |
|---|---|
| Gene Name | CHM |
| Organism | Homo sapiens (Human) |
| Gene Length | 653 |
| Protein Names | Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein) |
| Target Name | rab proteins geranylgeranyltransferase component a 1 |
| Target Type | Clinical trial target |
| Gene Age | >4290 ( ENSG00000188419 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P24386 |
| Gene Card | CHM |
| Uniprot ID | P24386 |
| Pfam | PF00996 |
| In ASD | no |
| Allosteric Prediction | no (-1.19232793) |
| Ortholog in Animals | Alpaca_ CHM ( ortholog_one2one ) Dog_ CHM ( ortholog_one2one ) GuineaPig_ CHM ( ortholog_one2one ) Macaque_ CHM ( ortholog_one2one ) Mouse_ Chm ( ortholog_one2one ) Pig_ CHM ( ortholog_one2one ) Rat_ Chm ( ortholog_one2one ) Rabbit_ CHM ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHML, GDI2, GDI1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.034778(Chimpanzee);0.001000(Mouse);NULL(Rat);0.011111(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs397514603 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:7957092}. |
| Mouse PG classification | NA |
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