| Gene Information | |
|---|---|
| Gene Name | CSF2RA |
| Organism | Homo sapiens (Human) |
| Gene Length | 400 |
| Protein Names | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (GM-CSF-R-alpha) (GMCSFR-alpha) (GMR-alpha) (CDw116) (CD antigen CD116) |
| Target Name | gm-csf receptor alpha subunit |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000198223 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P15509 |
| Gene Card | CSF2RA |
| Uniprot ID | P15509 |
| Pfam | PF18611; PF09240 |
| In ASD | no |
| Allosteric Prediction | yes (0.152422177) |
| Ortholog in Animals | Mouse_ Csf2ra ( ortholog_one2one ) Rat_ Csf2ra ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRLF1, IL13RA2, IL11RA, IL13RA1, CNTFR, IL2RG, CRLF2, IL31RA, IL3RA, IL6ST, IL12RB1, CSF3R, IL12RB2, GHR, IL6R, IL27RA, IL23R, LIFR, OSMR, IL5RA, EBI3, PRLR, LEPR |
| Tissue | whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NKQ (X-ray 3.30A ) 4RS1 (X-ray 2.68A ) |
| DBSNP | rs137852353 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted {ECO:0000305}.; [Isoform 4]: Secreted {ECO:0000305}.; [Isoform 6]: Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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