| Gene Information | |
|---|---|
| Gene Name | CHFR |
| Organism | Homo sapiens (Human) |
| Gene Length | 664 |
| Protein Names | E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000072609 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96EP1 |
| Gene Card | CHFR |
| Uniprot ID | Q96EP1 |
| Pfam | PF00498; PF10283; PF17979 |
| In ASD | no |
| Allosteric Prediction | yes (0.043783685) |
| Ortholog in Animals | Alpaca_ CHFR ( ortholog_one2one ) Dog_ CHFR ( ortholog_one2one ) GuineaPig_ CHFR ( ortholog_one2one ) Macaque_ CHFR ( ortholog_one2one ) Mouse_ Chfr ( ortholog_one2one ) Pig_ CHFR ( ortholog_one2one ) Rat_ Chfr ( ortholog_one2one ) Rabbit_ CHFR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10935642}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1LGP (X-ray 2.00A ) 1LGQ (X-ray 2.10A ) 2XOC (X-ray 1.89A ) 2XOY (X-ray 2.60A ) 2XOZ (X-ray 2.37A ) 2XP0 (X-ray 1.98A ) |
| DBSNP | rs1176037831 rs115096950 rs2306541 rs2306536 |
| Subcellular location [CC] | Nucleus, PML body {ECO:0000269|PubMed:11912157, ECO:0000269|PubMed:15467728, ECO:0000269|PubMed:18172500}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |