| Gene Information | |
|---|---|
| Gene Name | CHEMR23 |
| Organism | Homo sapiens (Human) |
| Gene Length | 373 |
| Protein Names | Chemerin-like receptor 1 (Chemokine-like receptor 1) (G-protein coupled receptor ChemR23) (G-protein coupled receptor DEZ) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q99788 |
| Gene Card | CMKLR1 |
| Uniprot ID | Q99788 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T-cells. Expressed on endothelial cells. Highly expressed in differentiating adipocytes. {ECO:0000269|PubMed:14530373, ECO:0000269|PubMed:15728234, ECO:0000269|PubMed:15753205, ECO:0000269|PubMed:18242188, ECO:0000269|PubMed:20044979, ECO:0000269|PubMed:8976386}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:15728234, ECO:0000269|PubMed:16863918, ECO:0000269|PubMed:27716822}; Multi-pass membrane protein {ECO:0000255}. Note=Internalizes efficiently in response to RARRES2. {ECO:0000269|PubMed:27716822}. |
| Mouse PG classification | NA |
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