| Gene Information | |
|---|---|
| Gene Name | SLC52A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 448 |
| Protein Names | Solute carrier family 52, riboflavin transporter, member 1 (Porcine endogenous retrovirus A receptor 2) (PERV-A receptor 2) (huPAR-2) (Protein GPR172B) (Riboflavin transporter 1) (hRFT1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000132517 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9NWF4 |
| Gene Card | SLC52A1 |
| Uniprot ID | Q9NWF4 |
| Pfam | PF06237 |
| In ASD | no |
| Allosteric Prediction | no (-1.029948189) |
| Ortholog in Animals | Alpaca_ SLC52A1 ( ortholog_one2one ) Dog_ SLC52A2 ( ortholog_one2one ) Macaque_ SLC52A1 ( ortholog_one2one ) Mouse_ Slc52a2 ( ortholog_one2many ) Rat_ Slc52a2 ( ortholog_one2many ) |
| Ohnologs | SLC52A2 |
| Paralogs | SLC52A2, SLC52A3 |
| Tissue | duodenum, placenta, skin, small.intestine |
| Tissue Specificity | Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues. {ECO:0000269|PubMed:12740431, ECO:0000269|PubMed:18632736, ECO:0000269|PubMed:20463145}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs346822 rs346821 rs2304445 rs187609896 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12740431, ECO:0000269|PubMed:18632736, ECO:0000269|PubMed:20463145}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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