| Gene Information | |
|---|---|
| Gene Name | CHD5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2715 |
| Protein Names | Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.12) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000116254 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | CHD6 |
| Uniprot ID | Q8TD26 |
| Pfam | PF00385; PF00271; PF00176 |
| In ASD | no |
| Allosteric Prediction | no (-0.125610975) |
| Ortholog in Animals | Alpaca_ CHD5 ( ortholog_one2one ) Dog_ CHD5 ( ortholog_one2one ) GuineaPig_ CHD5 ( ortholog_one2one ) Macaque_ CHD5 ( ortholog_one2one ) Mouse_ Chd5 ( ortholog_one2one ) Pig_ CHD5 ( ortholog_one2one ) Rat_ Chd5 ( ortholog_one2one ) |
| Ohnologs | CHD4, CHD3 |
| Paralogs | SMARCA1, RAD54B, HLTF, HELLS, SHPRH, BTAF1, ZRANB3, SMARCA5, TTF2, SMARCA2, CHD9, SMARCAL1, CHD1L, CHD3, RAD54L2, SMARCAD1, CHD4, ATRX, INO80, CHD6, SRCAP, CHD1, CHD2, RAD54L, CHD7, CHD8, EP400, ERCC6, ERCC6L, SMARCA4 |
| Tissue | brain, testis, cerebral.cortex |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.058983(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2EPB (NMR - ) |
| DBSNP | rs4474937 rs3817893 |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:17027977, ECO:0000269|PubMed:21899694}. Note=Enriched at sites of mRNA synthesis (PubMed:17027977). During influenza A virus infection, localizes to inactive chromatin. {ECO:0000269|PubMed:17027977, ECO:0000269|PubMed:21899694}. |
| Mouse PG classification | NA |
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