| Gene Information | |
|---|---|
| Gene Name | CHAT |
| Organism | Homo sapiens (Human) |
| Gene Length | 748 |
| Protein Names | Choline O-acetyltransferase (CHOACTase) (ChAT) (Choline acetylase) (EC 2.3.1.6) |
| Target Name | choline o-acetyltransferase |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000070748 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P28329 |
| Gene Card | CHAT |
| Uniprot ID | P28329 |
| Pfam | PF00755 |
| In ASD | no |
| Allosteric Prediction | yes (0.835943137) |
| Ortholog in Animals | Alpaca_ CHAT ( ortholog_one2one ) Dog_ CHAT ( ortholog_one2one ) GuineaPig_ CHAT ( ortholog_one2one ) Macaque_ CHAT ( ortholog_one2one ) Mouse_ Chat ( ortholog_one2one ) Pig_ CHAT ( ortholog_one2one ) Rabbit_ CHAT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRAT, CROT, CPT1B, CPT2, CPT1C, CPT1A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FY2 (X-ray 2.25A ) 2FY3 (X-ray 2.27A ) 2FY4 (X-ray 2.30A ) 2FY5 (X-ray 2.60A ) 7AMD (X-ray 2.25A ) |
| DBSNP | rs3810948 rs3810950 rs121912820 rs121912815 rs8178989 rs8178990 rs868749 rs75466054 rs121912823 rs8178991 rs121912822 rs121912816 rs4838544 rs121912818 rs121912821 rs121912817 rs121912819 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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