| Gene Information | |
|---|---|
| Gene Name | CHAD |
| Organism | Homo sapiens (Human) |
| Gene Length | 359 |
| Protein Names | Chondroadherin (Cartilage leucine-rich protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000136457 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O15335 |
| Gene Card | CHAD |
| Uniprot ID | O15335 |
| Pfam | PF00560; PF13855; PF01462 |
| In ASD | no |
| Allosteric Prediction | no (-0.830586933) |
| Ortholog in Animals | Alpaca_ CHAD ( ortholog_one2one ) Dog_ CHAD ( ortholog_one2one ) GuineaPig_ CHAD ( ortholog_one2one ) Macaque_ CHAD ( ortholog_one2one ) Mouse_ Chad ( ortholog_one2one ) Pig_ CHAD ( ortholog_one2one ) Rat_ Chad ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHADL, LRG1, CPN2, LRRTM2, LRRC52, LRIT3, LRRC24, ELFN2, LRIG3, LGR6, LGR5, LRIT1, TRIL, ELFN1, LGR4, LGI2, LGI1, LRIG2, LRRC26, LRIG1, LGI3, LGI4 |
| Tissue | NA |
| Tissue Specificity | Present in chondrocytes at all ages. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LFN (X-ray 2.10A ) 5MX1 (X-ray 2.17A ) |
| DBSNP | rs35218093 rs2231510 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Mouse PG classification | NA |
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