| Gene Information | |
|---|---|
| Gene Name | CHAC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 222 |
| Protein Names | Glutathione-specific gamma-glutamylcyclotransferase 1 (Gamma-GCG 1) (EC 4.3.2.7) (Blocks Notch protein) (Botch) (Cation transport regulator-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000128965 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BUX1 |
| Gene Card | CHAC1 |
| Uniprot ID | Q9BUX1 |
| Pfam | PF04752 |
| In ASD | no |
| Allosteric Prediction | yes (0.00983677) |
| Ortholog in Animals | Alpaca_ CHAC1 ( ortholog_one2one ) Dog_ CHAC1 ( ortholog_one2one ) GuineaPig_ CHAC1 ( ortholog_one2one ) Macaque_ CHAC1 ( ortholog_one2one ) Mouse_ Chac1 ( ortholog_one2one ) Pig_ CHAC1 ( ortholog_one2one ) Rat_ Chac1 ( ortholog_one2one ) Rabbit_ CHAC1 ( ortholog_one2one ) |
| Ohnologs | CHAC2 |
| Paralogs | CHAC2 |
| Tissue | esophagus, pancreas, skeletal.muscle |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:19109178}. Golgi apparatus, trans-Golgi network {ECO:0000250|UniProtKB:Q8R3J5}. |
| Mouse PG classification | NA |
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