| Gene Information | |
|---|---|
| Gene Name | SFTPB |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | Pulmonary surfactant-associated protein B (SP-B) (18 kDa pulmonary-surfactant protein) (6 kDa protein) (Pulmonary surfactant-associated proteolipid SPL(Phe)) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000168878 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P07988 |
| Gene Card | SFTPB |
| Uniprot ID | P07988 |
| Pfam | PF02199; PF05184; PF03489 |
| In ASD | no |
| Allosteric Prediction | no (-0.034003581) |
| Ortholog in Animals | Alpaca_ SFTPB ( ortholog_one2one ) Dog_ SFTPB ( ortholog_one2one ) GuineaPig_ SFTPB ( ortholog_one2one ) Macaque_ SFTPB ( ortholog_one2one ) Mouse_ Sftpb ( ortholog_one2one ) Pig_ SFTPB ( ortholog_one2one ) Rat_ Sftpb ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PSAPL1, PSAP |
| Tissue | lung |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DFW (IR - ) 1KMR (NMR - ) 1RG3 (NMR - ) 1RG4 (NMR - ) 1SSZ (IR - ) 2DWF (NMR - ) 2JOU (NMR - ) 2M0H (NMR - ) 2M1T (NMR - ) |
| DBSNP | rs1130866 rs3024801 rs137853202 rs3024809 |
| Subcellular location [CC] | Secreted, extracellular space, surface film. |
| Mouse PG classification | HPG |
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