| Gene Information | |
|---|---|
| Gene Name | SLC30A10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 485 |
| Protein Names | Zinc transporter 10 (ZnT-10) (Manganese transporter SLC30A10) (Solute carrier family 30 member 10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000196660 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q6XR72 |
| Gene Card | SLC30A10 |
| Uniprot ID | Q6XR72 |
| Pfam | PF01545 |
| In ASD | no |
| Allosteric Prediction | yes (0.234146102) |
| Ortholog in Animals | Alpaca_ SLC30A10 ( ortholog_one2one ) Dog_ SLC30A10 ( ortholog_one2one ) GuineaPig_ SLC30A10 ( ortholog_one2one ) Macaque_ SLC30A10 ( ortholog_one2one ) Mouse_ Slc30a10 ( ortholog_one2one ) Rat_ Slc30a10 ( ortholog_one2one ) Rabbit_ SLC30A10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC30A2, SLC30A3, SLC30A1, SLC30A7, SLC30A4, SLC30A6, SLC30A8, SLC30A5 |
| Tissue | colon, duodenum, liver, small.intestine |
| Tissue Specificity | Specifically expressed in fetal liver and fetal brain (PubMed:15154973). Expressed in adult tissues with relative levels small intestine > liver > testes > brain > ovary > colon > cervix > prostate > placenta (PubMed:22706290). {ECO:0000269|PubMed:15154973, ECO:0000269|PubMed:22706290}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs281860284 rs281860286 rs281860291 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:22706290, ECO:0000269|PubMed:25319704, ECO:0000269|PubMed:26728129}; Multi-pass membrane protein {ECO:0000305}. Golgi apparatus, trans-Golgi network {ECO:0000269|PubMed:22706290}. Recycling endosome {ECO:0000269|PubMed:22427991, ECO:0000269|PubMed:26728129}. Early endosome {ECO:0000269|PubMed:22427991}. Note=Relocalized from the trans-Golgi network to the plasma membrane upon elevated extracellular Zn concentrations (PubMed:22706290). {ECO:0000269|PubMed:22706290}. |
| Mouse PG classification | NA |
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