| Gene Information | |
|---|---|
| Gene Name | CGA |
| Organism | Homo sapiens (Human) |
| Gene Length | 116 |
| Protein Names | Glycoprotein hormones alpha chain (Anterior pituitary glycoprotein hormones common subunit alpha) (Choriogonadotropin alpha chain) (Chorionic gonadotrophin subunit alpha) (CG-alpha) (Follicle-stimulating hormone alpha chain) (FSH-alpha) (Follitropin alpha chain) (Luteinizing hormone alpha chain) (LSH-alpha) (Lutropin alpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha) (Thyrotropin alpha chain) |
| Target Name | glycoprotein hormones alpha |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000135346 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01215 |
| Gene Card | CGA |
| Uniprot ID | P01215 |
| Pfam | PF00236 |
| In ASD | no |
| Allosteric Prediction | no (-0.073039928) |
| Ortholog in Animals | Alpaca_ CGA ( ortholog_one2one ) Dog_ CGA ( ortholog_one2one ) GuineaPig_ GPA1 ( ortholog_one2one ) Macaque_ CGA ( ortholog_one2one ) Mouse_ Cga ( ortholog_one2one ) Pig_ CGA ( ortholog_one2one ) Rat_ Cga ( ortholog_one2one ) Rabbit_ GPA1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | placenta, pituitary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DZ7 (NMR - ) 1E9J (NMR - ) 1FL7 (X-ray 3.00A ) 1HCN (X-ray 2.60A ) 1HD4 (NMR - ) 1HRP (X-ray 3.00A ) 1QFW (X-ray 3.50A ) 1XWD (X-ray 2.92A ) 4AY9 (X-ray 2.50A ) 4MQW (X-ray 2.90A ) 7FIG (EM 3.90A ) 7FIH (EM 3.20A ) 7FII (EM 4.30A ) 7T9I (EM 2.90A ) 7UTZ (EM 2.40A ) 7XW5 (EM 2.96A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:24692546, ECO:0000269|PubMed:2494176}. |
| Mouse PG classification | NA |
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