| Gene Information | |
|---|---|
| Gene Name | CFP |
| Organism | Homo sapiens (Human) |
| Gene Length | 469 |
| Protein Names | Properdin (Complement factor P) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000126759 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P27918 |
| Gene Card | CFP |
| Uniprot ID | P27918 |
| Pfam | PF00090 |
| In ASD | no |
| Allosteric Prediction | yes (0.104405707) |
| Ortholog in Animals | Alpaca_ CFP ( ortholog_one2one ) Dog_ CFP ( ortholog_one2one ) GuineaPig_ CFP ( ortholog_one2one ) Macaque_ CFP ( ortholog_one2one ) Mouse_ Cfp ( ortholog_one2one ) Pig_ CFP ( ortholog_one2one ) Rat_ Cfp ( ortholog_one2one ) Rabbit_ CFP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | bone.marrow, spleen, lymph.node, whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.020000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1W0R (X-ray - ) 1W0S (X-ray - ) 6RUR (X-ray 6.00A ) 6RUS (X-ray 2.80A ) 6RUV (X-ray 6.15A ) 6RV6 (X-ray 3.51A ) 6S08 (X-ray 2.03A ) 6S0A (X-ray 2.52A ) 6S0B (X-ray 2.31A ) 6SEJ (X-ray 3.50A ) 7B26 (X-ray 3.40A ) 7NOZ (X-ray 3.90A ) |
| DBSNP | rs8177068 rs132630259 rs8177076 rs8177077 rs28935480 rs132630261 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:28264884, ECO:0000269|PubMed:31507604}. |
| Mouse PG classification | LPG |
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