| Gene Information | |
|---|---|
| Gene Name | CFAP65 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1925 |
| Protein Names | Cilia- and flagella-associated protein 65 (Coiled-coil domain-containing protein 108) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000181378 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6ZU64 |
| Gene Card | CFAP65 |
| Uniprot ID | Q6ZU64 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.730238196) |
| Ortholog in Animals | Alpaca_ CFAP65 ( ortholog_one2one ) Dog_ CFAP65 ( ortholog_one2one ) GuineaPig_ CFAP65 ( ortholog_one2one ) Macaque_ CFAP65 ( ortholog_one2one ) Mouse_ Cfap65 ( ortholog_one2one ) Pig_ CFAP65 ( ortholog_one2one ) Rat_ Cfap65 ( ortholog_one2one ) Rabbit_ CFAP65 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SOX12, SOX17, SOX13, SOX30, SOX21, SOX8, SOX7, SOX5, SOX14, SOX6, SOX9, SRY, SOX10, SOX1, SOX4, SOX18, SOX11, SOX3, SOX2, SOX15 |
| Tissue | testis, caudate.nucleus, medulla.oblongata |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6736922 rs13403802 rs9653262 rs11893183 |
| Subcellular location [CC] | Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:33472045}; Single-pass membrane protein {ECO:0000305}. Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000269|PubMed:31413122, ECO:0000269|PubMed:33472045}; Single-pass type I membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:31413122}. Note=Expressed in flagella midpiece and acrosome of mature spermatozoa. {ECO:0000269|PubMed:31413122, ECO:0000269|PubMed:33472045}. |
| Mouse PG classification | NA |
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